Advance in relationship between receptor gene abnormality and depression
10.16438/j.0513-4870.2019-0600
- VernacularTitle:抑郁症发病与受体基因异常研究进展
- Author:
Hui-qin WANG
1
,
2
;
Zhen-zhen WANG
3
;
Nai-hong CHEN
1
,
2
Author Information
1. Hunan Engineering Technology Center of Standardization and Function of Chinese Herbal Decoction Pieces, College of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China
2. Neuroscience Center, Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing 100050, China
3. Neuroscience Center, Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing 100050, China
- Publication Type:Research Article
- Keywords:
epression;
receptor;
receptor gene;
gene abnormality;
pathogenesis
- From:
Acta Pharmaceutica Sinica
2020;55(3):384-391
- CountryChina
- Language:Chinese
-
Abstract:
Depression, a chronic syndrome with low mood, pessimism, cognitive and sleep disorders, is characterized by high incidence, high suicide rate, low consultation and treatment rate. 40%-50% of the risk of depression comes from genes, so studying on gene abnormalities serves as an important part of the research in the internal causes of depression, among which the receptor gene abnormalities are crucial factors. The study of potential receptor gene loci is expected to be new target for the treatment of depression in the future, which can provide theoretical basis for the early diagnosis, prevention and treatment of depression.
