Development status and clinical applications of precision detection technology in the times of precision oncology
10.3872/j.issn.1007-385x.2020.02.001
- VernacularTitle:肿瘤精准医学时代下精准检测技术的发展现状与临床应用
- Author:
BAI Rilan
1
;
GUO Hanfei
1
;
CUI Jiuwei
1
Author Information
1. Cancer Center, the First Hospital of Jilin University
- Publication Type:Journal Article
- Keywords:
oncology;
precision medicine;
liquid biopsies;
next-generation sequencing (NGS);
single cell sequencing (SCS)
- From:
Chinese Journal of Cancer Biotherapy
2020;27(2):103-108
- CountryChina
- Language:Chinese
-
Abstract:
Precision detection techniques have promoted the development of individualized diagnosis and treatment of tumors in the era of precision medicine. At the same time, clinical demands of precision treatments have further driven the development and application of precision detection techniques. In recent years, precision medical detection techniques realized rapid transformations from low-throughput to high-throughput genomic sequencing, from tissue biopsies to liquid biopsies, and from multicell promiscuous detection to single cell precision sequencing. All these changes have promoted the emergence and development of new technologies, new targets, and new drugs in the era of precision oncology medicine. In the future, multi-dimensional combined detection could help to improve the accuracy of precision medicine; ctDNA methylation detection analysis could broaden the research field of precision medicine; and the transformation of clinical trial design could also contribute to promote the in-depth development of precision medicine.
- Full text:20200201.pdf
