Research progress in related gene of autosomal recessive cutis laxa

VernacularTitle:常染色体隐性遗传性皮肤松弛症的相关基因研究进展
Author: Wu-Juan SHI ^{1
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Author Information

1. Tianjin Children&rsquo
2. s Hospital, Tianjin 300134, China
3. 2 The Baodi District People&rsquo
4. s Hospital of Tianjin
Publication Type:Journal Article
Keywords: cutis laxa; mutation; signal transduction; autosomal recessive inheritance
From: Tianjin Medical Journal 2018;46(9):1027-1032
CountryChina
Language:Chinese
Abstract: Autosomal recessive cutis laxa is a common type of hereditary cutis laxa. Its pathogenesis is not completely clear, but involved genes and their corresponding functions and signaling pathways have gradually become the research focus. According to the latest research, the related genes and their responding signaling pathways not only provide a solid foundation for the pathogenesis of cutis laxa, but also indicate a direction for instructing healthy pregnancy and scientific nurture. This paper aims to review the recent advances in pathogenic genes and potential signaling pathways in autosomal recessive cutis laxa.