Pathological mechanisms of chronic insomnia: Evidence from neuro-electrophysiology and neuroimaging research.
10.11817/j.issn.1672-7347.2014.09.019
- Author:
Renzhi HUANG
1
;
Weihui LI
;
Lizhen SHE
;
Zexuan LI
;
Weixiong JIANG
Author Information
1. Department of Teaching Science, Hunan First Normal College, Changsha 410205,China.
- Publication Type:Journal Article
- MeSH:
Brain;
physiopathology;
Electrophysiology;
Gyrus Cinguli;
Hippocampus;
Humans;
Neuroimaging;
Prefrontal Cortex;
Sleep Initiation and Maintenance Disorders;
pathology;
Thalamus
- From:
Journal of Central South University(Medical Sciences)
2014;39(9):975-980
- CountryChina
- Language:Chinese
-
Abstract:
As a widely recognized public health problem as well as prevalent and challenging to modern society, chronic insomnia is involved in wide brain areas (such as prefrontal cortex, anterior cingulate cortex, amygdala, hippocampus, and thalamus) and emotion-cognition neuro-circuit. It is closely related to the conditioned hyperarousal and the increased information process and/or the impaired inhibitory ability to withdraw from awaking state. Thus, some specific abnormal mode may exist in the emotion-cognition circuit, which is associated with abnormal cognition load, such as repeated retrieval/intrusion of aversive memories during night. Studies through the combination of multiple techniques including psychology, electrophysiology and neuroimaging methods are needed to further enhance the understanding of chronic insomnia.
