Advance of adipose-derived stem cells in tendon tissue engineering.
10.11817/j.issn.1672-7347.2014.02.016
- Author:
Mingming YAN
1
;
Jiangdong NI
Author Information
1. Department of Orthopeadic Surgery, Second Xiangya Hospital, Central South University, Changsha 410011, China.
- Publication Type:Journal Article
- MeSH:
Adipocytes;
Adipose Tissue;
cytology;
Cell Differentiation;
Chondrocytes;
Humans;
Osteoblasts;
Stem Cells;
cytology;
Tendon Injuries;
therapy;
Tendons;
cytology;
Tissue Engineering;
Wound Healing
- From:
Journal of Central South University(Medical Sciences)
2014;39(2):199-203
- CountryChina
- Language:Chinese
-
Abstract:
Tendon tissue engineering is a novel therapeutic strategy for severe tendon injury and loss. Adipose derived stem cells (ASCs) have been studied extensively, due to their potency to differentiate into musculoskeletal tissue precursors such as osteoblasts, chondrocytes, adipocytes, and tendocytes under specific cues and high ability of proliferation. Resources of ASCs are ubiquitous and isolation of ASCs is secure, simple and minimally invasive. Mounting evidences demonstrate that ASCs may be involved in tendon tissue engineering and repair the severe injury of tendon under stimulation of various growth factors and other appropriate fittings.
