Nucleic acid aptamers in diagnosis of diseases.
10.11817/j.issn.1672-7347.2014.03.016
- Author:
Pan ZHANG
1
;
Kunhe ZHANG
Author Information
1. Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang 330006, China.
- Publication Type:Journal Article
- MeSH:
Aptamers, Nucleotide;
Diagnosis;
Disease;
Humans;
Sensitivity and Specificity
- From:
Journal of Central South University(Medical Sciences)
2014;39(3):320-323
- CountryChina
- Language:Chinese
-
Abstract:
Aptamers are single-stranded oligonucleotide ligands selected from a random pool of oligonucleotide sequences by systematic evolution of ligands by exponential enrichment. With the advantages of binding to targets with high specificity and affinity, aptamers have been used in the diagnosis widely, such as biochemistry detection, discovery of new tumor markers, molecular imaging, pathogenic and microorganism detection, showing a good application prospect.
