Progress in studies on the relationship between
Dicer and ovarian tumor.
10.11817/j.issn.1672-7347.2015.10.017
- Author:
Hua ZHAO
1
;
Huajiang SHAO
2
;
Jianting MA
2
Author Information
1. Medical School of Ningbo University, Ningbo Zhejiang 315000, China.
2. Department of Obstetrics & Gynecology, Yangming Hospital affiliated to Medical School of Ningbo University, Yuyao Zhejiang 315400, China.
- Publication Type:Journal Article
- MeSH:
DEAD-box RNA Helicases;
genetics;
Female;
Humans;
MicroRNAs;
genetics;
Ovarian Neoplasms;
genetics;
Prognosis;
Ribonuclease III;
genetics
- From:
Journal of Central South University(Medical Sciences)
2015;40(10):1156-1160
- CountryChina
- Language:Chinese
-
Abstract:
MiRNAs are short, noncoding RNAs that modulate gene expression at the posttranscriptional level and induce the degradation of the mRNA transcript or the inhibition of protein translation. Dicer is an endoribonuclease in the RNase III family that is essential for the production of miRNAs. The abnormal expression of Dicer is frequently found in the occurrence and development process of many kinds of tumors, which is closely related to the treatment and prognosis of tumor.
