Portopulmonary hypertension with recurrent syncope:
a case report and review of literature.
10.11817/j.issn.1672-7347.2015.10.018
- Author:
Mengling HOU
1
;
Ling LIU
1
;
Daoquan PENG
1
;
Jiang LI
1
Author Information
1. Department of Cardiology, Second Xiangya Hospital, Central South University, Changsha 410011, China.
- Publication Type:Case Reports
- MeSH:
Blood Pressure;
Humans;
Hypertension, Portal;
complications;
diagnosis;
Hypertension, Pulmonary;
complications;
diagnosis;
Liver Transplantation;
Syncope;
complications;
diagnosis
- From:
Journal of Central South University(Medical Sciences)
2015;40(10):1161-1164
- CountryChina
- Language:Chinese
-
Abstract:
A case of portopulmonary hypertension characterized by repeated syncope was retrospectively analyzed. Intrahepatic or extrahepatic factor-induced portal hypertension complicated with metabolic disorder of vasoactive substances, vascular pressure, inflammation, etc. may result in systolic and diastolic dysfunction of pulmonary arteries and systemic hyperdynamic circulation, the long-term effect of which can induce vascular remodeling and consequently, pulmonary hypertension. The pathogenic process is rather insidious. Pulmonary hypertension is clinically characterized by the raised average pulmonary artery pressure, normal pulmonary capillary wedge pressure and high pulmonary vascular resistance. Currently available therapeutic approaches include drug therapy targeting on pulmonary hypertension and liver transplantation.
