Clinical value in detection of blood miRNAs in patients with colorectal cancer.
10.11817/j.issn.1672-7347.2015.11.019
- Author:
Yan TAN
1
;
Furong LI
2
;
Xiaofang YU
1
Author Information
1. Department of Hepatopancreatobiliary Surgery, Second Clinic Medicine College, Jinan University, Shenzhen People's Hospital, Shenzhen Guangdong 518020, China.
2. Translational Medicine Research Center, Second Clinic Medicine College, Jinan University, Shenzhen People's Hospital, Shenzhen Guangdong 518020, China.
- Publication Type:Journal Article
- MeSH:
Biomarkers, Tumor;
blood;
Carcinogenesis;
Colorectal Neoplasms;
blood;
Early Detection of Cancer;
Humans;
MicroRNAs;
blood;
Prognosis
- From:
Journal of Central South University(Medical Sciences)
2015;40(11):1276-1280
- CountryChina
- Language:Chinese
-
Abstract:
Colorectal cancer (CRC) is the most common cancer in digestive system, with the highest mortality rate. Its pathogenesis, diagnosis and treatment have been studied extensively. With the deepening of the investigations, more and more studies show that miRNA is closely related with the carcinogenesis, diagnosis and treatment of CRC. The abnormal expression of blood miRNA is expected to become the biomarkers for early diagnosis of CRC and prognostic evaluation, and it may provide a new strategy for clinical treatment.
