Progress in studies on JNK signaling pathway and autophagy.
10.11817/j.issn.1672-7347.2015.09.015
- Author:
Fang QIN
1
;
Zhibo ZHANG
2
Author Information
1. Affiliated Changsha Hospital, University of South China, Changsha 410005, China.
2. Department of Neurology, First Hospital of Changsha, Changsha 410005, China.
- Publication Type:Journal Article
- MeSH:
Autophagy;
Humans;
JNK Mitogen-Activated Protein Kinases;
MAP Kinase Signaling System
- From:
Journal of Central South University(Medical Sciences)
2015;40(9):1035-1038
- CountryChina
- Language:Chinese
-
Abstract:
JNK signaling pathway plays an important role in regulation of cell growth, proliferation, differentiation, migration and apoptosis. Studies have shown that JNK signaling pathway is closely related to autophagy, but the underlying mechanisms are not clear. Clarification of the correlation between the JNK signaling pathway and autophagy may provide opportunities for identifying potential molecular targets for the treatment of diseases associated with autophagy.