Monitoring of 4 patients with heparin-induced thrombocytopenia after complex congenital heart surgery.
10.11817/j.issn.1672-7347.2015.09.016
- Author:
Jianhui ZHOU
1
;
Jing PENG
2
;
Qian LI
1
;
Sisi WEI
1
;
Wenya WU
1
Author Information
1. Department of Cardiovascular Surgery, Xiangya Hospital, Central South University, Changsha 410008, China.
2. Department of Paediatrics, Xiangya Hospital, Central South University, Changsha 410008, China.
- Publication Type:Journal Article
- MeSH:
Anticoagulants;
adverse effects;
Cardiac Surgical Procedures;
Heparin;
adverse effects;
Humans;
Incidence;
Infant;
Pipecolic Acids;
therapeutic use;
Platelet Count;
Prognosis;
Thrombocytopenia;
chemically induced;
Thrombosis
- From:
Journal of Central South University(Medical Sciences)
2015;40(9):1039-1042
- CountryChina
- Language:Chinese
-
Abstract:
From July 2013 to February 2015, 4 infant patients with complex congenital heart disease, who underwent open heart surgery in Xiangya Hospital of Central South University, were diagnosed as heparin-induced thrombocytopenia (HIT). After comprehensive treatments, such as intensive monitoring of the platelet count, close observation of thromboembolic skin lesions and close monitoring of argatroban therapy, 3 patients were cured and 1 died. HIT is rare but serious in patients who received heparin therapy. The incidence of mortality and thrombosis is very high. Early identification and diagnosis of high-risk groups can improve the prognosis.