Risk factors for schizophrenia patients with type 2 diabetes: a metaanalysis.
10.11817/j.issn.1672-7347.2015.03.002
- Author:
Min ZHOU
1
;
Chuan XIAO
;
Min YANG
;
Ping YUAN
;
Yuanyuan LIU
Author Information
1. Department of Epidemiology and Biostatistics, West China School of Public Health, Sichuan University, Chengdu 610041, China.
- Publication Type:Journal Article
- MeSH:
China;
Diabetes Mellitus, Type 2;
epidemiology;
Female;
Humans;
Male;
Overweight;
epidemiology;
Risk Factors;
Schizophrenia;
epidemiology
- From:
Journal of Central South University(Medical Sciences)
2015;40(3):241-249
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate risk factors for schizophrenia patients with complication of type 2 diabetes mellitus and to provide scientific evidence for prevention and management of this disease.
METHODS:Relevant studies on schizophrenia with type 2 diabetes mellitus in China were searched through PubMed, Medline, CBM, CNKI and VIP from 1997 to 2014. Meta-analysis was performed using RevMan 5.2 soft ware.
RESULTS:A total of 26 studies involving 6 373 participants (including 957 cases and 5 416 controls) were included. The results of Meta-analysis showed that the risk factors for schizophrenic patients with complication of type 2 diabetes mellitus were: gender (female) (OR=1.28, 95%CI: 1.09-1.50), age (≥ 40 year) (OR=6.02, 95%CI: 4.48-8.09), overweight (OR=2.32, 95%CI: 1.52-2.88), family history of diabetes (OR=6.12, 95%CI: 3.16-11.86), duration of schizophrenia (>10 years) (OR=3.60, 95%CI: 2.39-5.41), triglycerides (MD=0.38, 95%CI: 0.05-0.71).
CONCLUSION:Male, old age, overweight, family history of diabetes, longer duration and high level of triglycerides are risk factors for schizophrenic patients with complication of diabetes mellitus.
