Progress in regulatory T cells and hepatocellular carcinoma.
10.11817/j.issn.1672-7347.2015.04.016
- Author:
Siqing JIANG
1
;
Dawei PENG
;
Lixiang HE
Author Information
1. Department of Oncology, Affi liated Haikou Hospital, Xiangya School of Medicine, Central South University, Haikou 570208, China.
- Publication Type:Journal Article
- MeSH:
Carcinoma, Hepatocellular;
immunology;
Disease Progression;
Humans;
Liver Neoplasms;
T-Lymphocytes, Regulatory
- From:
Journal of Central South University(Medical Sciences)
2015;40(4):433-437
- CountryChina
- Language:Chinese
-
Abstract:
As a functionally unique subset of T cells, regulatory T cells (Treg) suppress tumor immune responses effectively through a variety of mechanisms and play an important role in tumorigenesis and tumor progression. There is growing evidence to suggest that Treg participates in the formation and development of hepatic tumor, especially the HCC. Elucidation of the mechanisms for involvement of Treg in HCC progression may provide new ideas for liver cancer therapy through a point of view regarding immunology.
