Evaluation of risk factors and prognosis on diodone-induced acute kidney injury according to ESUR and KDIGO criteria.
10.11817/j.issn.1672-7347.2016.01.010
- Author:
Nana WANG
1
;
Qian XU
2
;
Shaobin DUAN
2
;
Rong LEI
2
;
Jun GUO
2
Author Information
1. Department of Nephrology, Second People's Hospital, Hefei 230000, China.
2. Department of Nephrology,Second Xiangya Hospital, Central South University; Renal Stem Cell Laboratory, Nephrology Institute, Central South University, Changsha 410011, China.
- Publication Type:Journal Article
- MeSH:
Acute Kidney Injury;
chemically induced;
diagnosis;
mortality;
Angiography;
Contrast Media;
adverse effects;
Dehydration;
epidemiology;
Diabetes Mellitus;
epidemiology;
Humans;
Incidence;
Iodopyracet;
adverse effects;
Logistic Models;
Prognosis;
Renal Insufficiency, Chronic;
epidemiology;
Risk Factors
- From:
Journal of Central South University(Medical Sciences)
2016;41(1):65-70
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the incidence, risk factors and prognosis for contrast-induced acute kidney injury (CI-AKI) according to ESUR and KDIGO criteria in patients undergoing angiography.
METHODS:We evaluated 260 patients undergoing angiography and/or intervention therapy from April 2011 to January 2012 in the Second Xiangya Hospital of Central South University. All patients received low-osmolality contrast agent (ioversol). Serum creatinine was measured before angiography or at 48 or 72 h after procedure. The multivariate logistic regression was used to analyze the risk factors of CI-AKI. The major adverse events were observed in a year of follow-up.
RESULTS:Among the 260 patients, 23 experienced CI-AKI and the incidence was 8.8% according to ESUR criteria. Twelve patients experienced CI-AKI and the incidence was 4.6% according to KDIGO criteria. The multivariate logistic regression analysis showed that diabetes mellitus and dehydration were the independent risk factors for CI-AKI according to ESUR criteria; In another KDIGO criteria, chronic kidney disease (CKD), hypercholesterolemia and diabetes mellitus were the independent risk factors for CI-AKI. The prognosis study showed that the mortality of patients with CI-AKI were significantly higher than those without CI-AKI (P<0.05).
CONCLUSION:The incidence of CI-AKI is associated with diagnostic criteria. Diabetes mellitus, CKD, dehydration and hypercholesterolemia were the independent risk factors for CI-AKI. CI-AKI is a relevant factor for mortality in a year after angiography and/or intervention therapy.
