Evaluation of risk factors and prognosis on diodone-induced acute kidney injury according to ESUR and KDIGO criteria.
10.11817/j.issn.1672-7347.2016.01.010
- Author:
Nana WANG
1
;
Qian XU
2
,
3
;
Shaobin DUAN
2
,
3
;
Rong LEI
2
,
3
;
Jun GUO
2
,
3
Author Information
1. Department of Nephrology, Second People's Hospital, Hefei 230000, China.
2. Department of Nephrology,Second Xiangya Hospital, Central South University
3. Renal Stem Cell Laboratory, Nephrology Institute, Central South University, Changsha 410011, China.
- Publication Type:Journal Article
- MeSH:
Acute Kidney Injury;
chemically induced;
diagnosis;
mortality;
Angiography;
Contrast Media;
adverse effects;
Dehydration;
epidemiology;
Diabetes Mellitus;
epidemiology;
Humans;
Incidence;
Iodopyracet;
adverse effects;
Logistic Models;
Prognosis;
Renal Insufficiency, Chronic;
epidemiology;
Risk Factors
- From:
Journal of Central South University(Medical Sciences)
2016;41(1):65-70
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the incidence, risk factors and prognosis for contrast-induced acute kidney injury (CI-AKI) according to ESUR and KDIGO criteria in patients undergoing angiography.
METHODS:We evaluated 260 patients undergoing angiography and/or intervention therapy from April 2011 to January 2012 in the Second Xiangya Hospital of Central South University. All patients received low-osmolality contrast agent (ioversol). Serum creatinine was measured before angiography or at 48 or 72 h after procedure. The multivariate logistic regression was used to analyze the risk factors of CI-AKI. The major adverse events were observed in a year of follow-up.
RESULTS:Among the 260 patients, 23 experienced CI-AKI and the incidence was 8.8% according to ESUR criteria. Twelve patients experienced CI-AKI and the incidence was 4.6% according to KDIGO criteria. The multivariate logistic regression analysis showed that diabetes mellitus and dehydration were the independent risk factors for CI-AKI according to ESUR criteria; In another KDIGO criteria, chronic kidney disease (CKD), hypercholesterolemia and diabetes mellitus were the independent risk factors for CI-AKI. The prognosis study showed that the mortality of patients with CI-AKI were significantly higher than those without CI-AKI (P<0.05).
CONCLUSION:The incidence of CI-AKI is associated with diagnostic criteria. Diabetes mellitus, CKD, dehydration and hypercholesterolemia were the independent risk factors for CI-AKI. CI-AKI is a relevant factor for mortality in a year after angiography and/or intervention therapy.
