Recent advances in the pharmacotherapy of psychiatric disorders.
10.5124/jkma.2011.54.10.1061
- Author:
Young Sup WOO
1
;
Won Myong BAHK
Author Information
1. Department of Psychiatry, Yeouido St. Mary's Hospital, The Catholic University of Korea College of Medicine, Seoul, Korea. wmbahk@catholic.ac.kr
- Publication Type:Original Article
- Keywords:
Psychopharmacology;
Antipsychotics;
Mood stabilizers;
Anticonvulsants;
Antidepressive agents
- MeSH:
Aripiprazole;
Amines;
Anticonvulsants;
Antidepressive Agents;
Antipsychotic Agents;
Anxiety Disorders;
Benzodiazepines;
Bipolar Disorder;
Carbamazepine;
Clozapine;
Cyclohexanecarboxylic Acids;
Depression;
Dibenzothiazepines;
Dibenzothiepins;
Fructose;
gamma-Aminobutyric Acid;
Heterocyclic Compounds with 4 or More Rings;
Lurasidone Hydrochloride;
Isoindoles;
Isoxazoles;
Nipecotic Acids;
Quetiapine Fumarate;
Pharmacology, Clinical;
Pregabalin;
Piperazines;
Piperidines;
Piracetam;
Psychopharmacology;
Pyrimidines;
Quinolones;
Risperidone;
Sulpiride;
Thiazoles;
Treatment Outcome;
Triazines;
Vigabatrin
- From:Journal of the Korean Medical Association
2011;54(10):1061-1069
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Psychopharmacology has developed over approximately the past five decades. The remarkable proliferation of information in this area has made it difficult for clinicians to understand the characteristics of various psychotropic agents. Atypical antipsychotics including amisulpride, asenapine, aripiprazole, blonanserin, clozapine, iloperidone, lurasidone, olanzapine, paliperidone, quetiapine, risperidone, ziprasidone, and zotepine cause fewer extrapyramidal problems and have many clinical applications, but they can cause metabolic disturbances. Mood stabilizers and lamotrigine are widely used for bipolar disorder. Other novel anticonvulsants such as topiramate, oxcarbazepine, gabapentin, tiagabine, pregabalin, vigabatrin, levetiracetam, and riulzole have also been tested with diverging or inconclusive results. Antidepressants are commonly used in the clinical treatment of depression and anxiety disorder. However, the mechanism of action of medications used in the treatment of psychiatric disorders remains unclear. Understanding the mechanisms of action and clarifying the diagnosis may enhance the treatment outcome in psychiatry. In this review, we analyzed clinical pharmacology data for each drug within a class and discussed clinical strategies for administering currently available antipsychotics, mood stabilizer/anticonvulsants, and antidepressants widely used for various psychiatric indications.
