MicroRNA and metabolism regulation.
10.3969/j.issn.1672-7347.2013.03.017
- Author:
Ming LI
1
;
Huiqing XIE
;
Wu XIONG
;
Dan XU
;
Ke CAO
;
Rui LIU
;
Jianda ZHOU
;
Chengqun LUO
Author Information
1. Department of Plastics Surgery, Third Xiangya Hospital, Central South University, Changsha 410013, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Glucose;
metabolism;
Glutamine;
metabolism;
Humans;
Insulin;
metabolism;
Insulin Secretion;
Lipid Metabolism;
physiology;
Metabolism;
physiology;
MicroRNAs;
physiology
- From:
Journal of Central South University(Medical Sciences)
2013;38(3):318-322
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNAs have been identified as a new class of regulatory molecules that affect many biological functions by interferring the target gene expressions. Latest studies demonstrate that microRNAs can influence many pivotal bio-processes and deeply involve in the metabolism of glucose, lipid and amino acid and biological oxidation. For glucose metabolism, microRNAs are related to insulin secretion, insulin sensitivity, glucose uptake, glycolysis, oxidation and mitochondrial function. For lipid matebolism, microRNAs can regulate the target genes related to lipid biosynthesis, catabolism and transportation. MicroRNAs can influence glutamine catabolism.
