Influence of endoscopic variceal ligation on liver function and risk factors of rebleeding.
10.3969/j.issn.1672-7347.2013.05.013
- Author:
Fen WANG
1
;
Guangkui BU
;
Shourong SHEN
;
Wuliang TANG
;
Canxia XU
Author Information
1. Department of Gastroenterology, Third Xiangya Hospital, Central South University, Changsha 410013, China.
- Publication Type:Journal Article
- MeSH:
Adult;
Endoscopy;
methods;
Esophageal and Gastric Varices;
etiology;
surgery;
Female;
Gastrointestinal Hemorrhage;
etiology;
prevention & control;
surgery;
Humans;
Ligation;
methods;
Liver;
physiopathology;
Liver Cirrhosis;
complications;
etiology;
physiopathology;
Logistic Models;
Male;
Middle Aged;
Recurrence;
Risk Factors;
Secondary Prevention
- From:
Journal of Central South University(Medical Sciences)
2013;38(5):521-525
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the influence of endoscopic variceal ligation (EVL) on liver function and analyze the risk factors of rebleeding after EVL.
METHODS:A total of 137 cirrhotic patients with esophageal varices who received EVL were retrospectively analyzed, and divided into group A, B, and C according to the Child-Pugh scores of liver function. We compared the liver function 1 week preoperatively and postoperatively. The patients were further divided into a rebleeding group and a non-rebleeding group after the EVL, and risk factors about rebleeding were analyzed.
RESULTS:There was no significant difference on ALT, AST, T-Bil, and D-Bil either preoperatively or postoperatively in group A, B, and C (P>0.05). Thirteen patients (9.49%) rebled after the EVL. The course of disease, liver function, prothrombin time, and mass ascites were the risk factors of rebleeding.
CONCLUSION:EVL has no obvious effect on liver function, and the course of disease, liver function, prothrombin time and mass ascites are risk factors of rebleeding after EVL.
