Histomorphological analyse of accelerating the fibrocartilage layer repair of patella-patellar tendon junction in rabbits by low intensity pulsed ultrasound stimulation.
10.3969/j.issn.1672-7347.2013.08.013
- Author:
Baoliang ZHANG
1
,
2
;
Hongbin LÜ
;
Jianzhong HU
;
Daqi XU
;
Jingyong ZHOU
;
Ye WANG
Author Information
1. Department of Sports Medicine, Xiangya Hospital, Central South University, Changsha 410008
2. Department of Spinal Surgery, Central Hospital of Yongzhou, Yongzhou Hunan 425000,China.
- Publication Type:Journal Article
- MeSH:
Animals;
Female;
Fibrocartilage;
pathology;
physiopathology;
Patella;
surgery;
Patellar Ligament;
injuries;
pathology;
physiopathology;
surgery;
Rabbits;
Tendon Injuries;
therapy;
Ultrasonic Therapy;
methods;
Wound Healing;
physiology
- From:
Journal of Central South University(Medical Sciences)
2013;38(8):838-842
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To analyse the effect of low intensity pulsed ultrasound stimulation (LIPUS) on accelerating the fibrocartilage layer repair of patella-patellar tendon junction.
METHODS:A total of 60 mature female New Zealand white rabbits undergoing standard partial patellectomy were divided into 2 groups randomly. The control group was given comfort treatment and the treatment group was given LIPUS treatment starting from day 3 to the end of week 6 postoperatively. The scheduled time points of animal euthanization would be at week 6, week 12 and week 18 postoperatively. The patella-patellar tendon (PPT) complex would be harvested and cut into sections after decalcification for H&E staining, Safranine o/fast green staining. The thickness and gray value of fibrocartilage layer were analyzed by SANO Microscope Partner image analyzer.
RESULTS:At week 6, week 12 and week 18 postoperatively, the fibrocartilage layer in the treatment group was significantly thicker than that in the control group (P<0.01), and the gray value of fibrocartilage layer was significantly smaller than that in the control group (P<0.01).
CONCLUSION:LIPUS helps to accelerate the fibrocartilage layer repair of patella-patellar tendon junction in rabbit models.
