Case-control study on the risk factors of type 2 diabetes of Dong nationality in Western Hunan.
10.3969/j.issn.1672-7347.2013.10.013
- Author:
Liya LIU
1
,
2
;
Lizhang CHEN
;
Jinxiong DAI
;
Jiaxiong CHEN
;
Ying LIANG
;
Tingli PEI
;
Yongbin HUANG
Author Information
1. School of Public Health, Central South University, Changsha 410078
2. Department of Medical Laboratory, Huaihua Medical College, Huaihua Hunan 418000,China.
- Publication Type:Journal Article
- MeSH:
Blood Glucose;
Body Mass Index;
Case-Control Studies;
China;
epidemiology;
Diabetes Mellitus, Type 2;
epidemiology;
ethnology;
Ethnic Groups;
Glucose Tolerance Test;
Humans;
Insulin;
Insulin Resistance;
Insulin-Secreting Cells;
Lipids;
Obesity;
Overweight;
Risk Factors;
Socioeconomic Factors
- From:
Journal of Central South University(Medical Sciences)
2013;38(10):1057-1064
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To explore the risk factors of type 2 diabetes mellitus (T2DM) of Dong nationality in Western Hunan, and to provide a scientific basis for the prevention and treatment of T2DM in the district.
METHODS:In the case-control study, the subjects were divided into a T2DM group, an impaired glucose regulation (IGR) group and a normal glucose tolerance (NGT) group through oral glucose tolerance test (OGTT). A questionnaire survey was conducted, and physical measurements and the detection of blood glucose, blood lipids and serum insulin were done.
RESULTS:Univariate analysis found significant difference in age, fasting insulin (FINS), HOMA insulin resistance index (HOMA-IRI), HOMA β-cell function index (HOMA-βC), trigalloyl glycerol (TG), high density lipoprotein cholesterol (HDL-C), systolic blood pressure, and diastolic blood pressure in the glucose metabolism among different groups (P<0.05). Body mass index (BMI), waist/hip ratio (WHR), family history of diabetes, number of physical activities per week, dinner taste, fat and protein-rich foods, fresh vegetables and fruits intake were associated with T2DM. Multifactor non-conditional ordinal logistic regression indicated that age was the risk factor of T2DM and IGR. Compared with the group whose age was≤50, the odds ratios of the groups of 5070 were 1.85, 2.83 and 2.64 respectively, P<0.05. The risk of suffering from diabetes of the overweighted or obese people was 2.13 times that of a normal BMI group, P<0.01. The other influencing factors included WHR (OR=2.06), family history of diabetes (OR=11.36), and fat and protein-rich foods (OR=1.90).
CONCLUSION:The main influencing factors of T2DM of Dong nationality in Western Hunan include age, BMI, WHR, family history of diabetes, fat and protein-rich foods. We must strengthen the health eduation of T2DM of Dong nationality in Western Hunan to reduce the risk of T2DM.
