Genetic polymorphism of 19 STR loci in Xinjiang Barkol Kazakh population.
- Author:
Liping ZHANG
1
;
Chenbo XU
;
Huijin CHEN
;
You ZHOU
;
Fei LI
;
Jiangang CHEN
Author Information
1. Department of Biochemistry and Molecular Biology, Xinjiang Medical University, Urumqi, China.
- Publication Type:Journal Article
- MeSH:
Asian Continental Ancestry Group;
genetics;
China;
Forensic Genetics;
Gene Frequency;
Genetic Loci;
Genetics, Population;
Humans;
Microsatellite Repeats;
genetics;
Polymorphism, Genetic
- From:
Journal of Central South University(Medical Sciences)
2012;37(9):934-938
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate 19 short tandem repeat (STR) loci in Chinese Kazakh population in Barkol County with Goldeneye™20A multiplex amplification system.
METHODS:DNA samples were screened from 81 unrelated individuals. The 19 loci were D8S1179, D21S11, CSF1PO, D3S1358, D7S820, TH01, D13S317, D2S1338, D18S51, D16S539, TPOX, vWA, D19S433, D5S818, PentaD, PentaE, D6S1043, D12S391 and FGA. The PCR products were analyzed and genotyped by ABI3130XL sequencer.
RESULTS:These loci were highly polymorphic. The combined power of discrimination was 0.999999999 and the combined paternity of exclusion was 0.999998914.
CONCLUSION:Goldeneye™20A multiplex amplification system is very useful in forensic case investigation for Barkol Kazakh population.
