Repeated Panniculitis Induced by Pegylated Interferon Alpha 2a in a Patient with Chronic Hepatitis C.
10.4166/kjg.2016.67.5.272
- Author:
June Seok SONG
1
;
Joo Hyun SOHN
;
Jae Yoon JEONG
;
Ji Hee MIN
;
Won Seok CHOI
;
One Zoong KIM
;
Ju Yeon PYO
Author Information
1. Department of Internal Medicine, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Korea. sonjh@hanyang.ac.kr
- Publication Type:Case Report
- Keywords:
Panniculitis;
Peginterferon alfa-2a;
Hepatitis C;
Adverse effects
- MeSH:
Hepatitis C;
Hepatitis C, Chronic*;
Hepatitis, Chronic*;
Humans;
Interferon-alpha*;
Interferons*;
Panniculitis*;
Ribavirin;
Withholding Treatment
- From:The Korean Journal of Gastroenterology
2016;67(5):272-276
- CountryRepublic of Korea
- Language:English
-
Abstract:
Pegylated interferon alpha (PEG-IFN-α) is widely used to treat chronic hepatitis C in combination with ribavirin. Many adverse effects of PEG-IFN-α, such as hematologic, psychologic, dermatologic, immunologic, and other abnormalities, have been reported, and some serious adverse events lead to PEG-IFN-α treatment discontinuation. For very rare adverse events such as panniculitis, there are no established guidelines on whether to continue PEG-IFN-α treatment. Published reports on panniculitis induced by PEG-IFN-α 2a are sparse. Herein we report a case of repeated occurrences of panniculitis in a patient with chronic hepatitis C, leading to treatment cessation.
