Research progress with renalase and cardiovascular disease.
10.3969/j.issn.1672-7347.2012.05.021
- Author:
Yunzhong GUO
1
;
Weihong JIANG
Author Information
1. Department of Cardiology, Central South University, Changsha, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Cardiovascular Diseases;
physiopathology;
Heart Failure;
physiopathology;
Humans;
Hypertension;
physiopathology;
Monoamine Oxidase;
genetics;
physiology;
Myocardial Ischemia;
physiopathology
- From:
Journal of Central South University(Medical Sciences)
2012;37(5):537-540
- CountryChina
- Language:Chinese
-
Abstract:
Renalase, a novel amine oxidase, is secreted by kidney. It regulates heart function and blood pressure by degrading catecholamines. Hormones secreted by the kidney are associated with cardiovascular disease. Renalase, as a new biomarker of heart and kidney functional correlation, can lower blood pressure, protect ischemic heart muscle, improve heart function and degrade catecholamine.