Retrospective analysis of treatment for severe ovary hyperstimulation syndrome complicated by pleural effusion and ascites.
10.3969/j.issn.1672-7347.2012.07.013
- Author:
Fei GONG
1
;
Hui GUO
;
Yan SHEN
;
Juan LI
;
Guangxiu LU
;
Ge LIN
Author Information
1. Institute of Reproduction and Stem Cell, Central South University, Changsha, China.
- Publication Type:Journal Article
- MeSH:
Adult;
Ascites;
etiology;
therapy;
Dextrans;
administration & dosage;
Drainage;
Female;
Fertilization in Vitro;
Humans;
Hydroxyethyl Starch Derivatives;
administration & dosage;
Infusions, Intravenous;
Ovarian Hyperstimulation Syndrome;
complications;
therapy;
Ovulation Induction;
adverse effects;
Pleural Effusion;
etiology;
therapy;
Retrospective Studies;
Serum Albumin;
administration & dosage
- From:
Journal of Central South University(Medical Sciences)
2012;37(7):720-724
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the effectiveness of treatment for severe ovary hyperstimulation syndrome (OHSS) complicated by pleural effusion and ascites after in vitro fertilization preembryo transfer (IVF-ET).
METHODS:One hundred and thirty-two patients with severe OHSS in our hospital (from January 2007 to December 2010) were retrospectively analyzed and the efficacy of three therapeutic methods was compared. Twenty-five patients in group I were treated with low-molecular dextran and albumin, 67 patients in group II were treated with 6% medium molecular-weight hydroxyethyl starch, and 40 patients in group III were treated with active aspiration of pleural effusion and ascites.
RESULTS:All three therapies improved the symptoms of OHSS and various blood biochemical parameters. The duration of hospitalization of group III [(7.4±4.5) d] was significantly less than those of group I [(21.4±9.2) d] or II [(15.6±6.7) d], and the cost of group III [(2656.2±1882.8) Yuan] was also significantly lower than that of group I or II [(11937.6±7989.8) and (5182.7±2991.7) Yuan, respectively].
CONCLUSION:Abdominal B ultrasonography-guided trans-abdominal wall aspiration of pleural effusion and ascites combined with blood volume maintenance is an effective and economical way to treat OHSS.
