Effect of two short striae incision or traditional "L" shaped incision in neck dissection of differentiated thyroid carcinoma on serum trauma cytokines.
10.3969/j.issn.1672-7347.2012.12.014
- Author:
Zhongli GENG
1
;
Wei WANG
;
Meihui SHAN
;
Guanghui REN
;
Chao DONG
;
Binlin MA
Author Information
1. Department of Mammary Gland, Tumor Hospital of Xinjiang Medical University, Urumqi, China.
- Publication Type:Journal Article
- MeSH:
Adult;
C-Reactive Protein;
metabolism;
Carcinoma, Papillary;
blood;
surgery;
Cytokines;
blood;
Female;
Humans;
Interleukin-2;
blood;
Interleukin-6;
blood;
Male;
Middle Aged;
Neck Dissection;
methods;
Thyroid Neoplasms;
blood;
surgery
- From:
Journal of Central South University(Medical Sciences)
2012;37(12):1260-1264
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To compare the trauma of neck dissection on the human body between two-striae incision and traditional "L" shaped incision by serum trauma cytokines.
METHODS:Patients with differentiated thyroid carcinoma hospitized from December 2008 to July 2011 were divided into 2 groups according to their own will. The first group 26 patients) had two-striae incision and the second group 32 patients) had traditional "L" shaped incision. The serum level of interleukin(IL)-2, IL-6 and C-reactive protein (CRP) in all patients were examined 1 day before and 1, 3 and 5 days after the surgery.
RESULTS:No statistical significance was found between the 2 groups, although level of IL-2 decreased 1 day after the surgery, but recovered to normal 3 days later. The level of IL-6 in both groups increased 1 day after the surgery, began to decrease 3 days after the surgery, and recovered to normal 5 days after the surgery. The level of CRP suggested statistical significance (P<0.05), which increased obviously 1, 3 and 5 days after the surgery. No statistical difference was found before or after the surgery between the 2 groups (P>0.05). After follow-up for 8-40 months, no local recurrence or lymph node metastasis was found.
CONCLUSION:Compared with the traditional "L" shaped incision, two-striae incision in neck dissection does not increase the serum level of trauma cytokines and trauma to human body after the surgery. Two-striae incision is an ideal surgical approach to differentiated thyroid carcinoma.
