Therapeutic effect of Rabdosia rubescens aqueous extract on chronic pharyngitis and its safety.
10.3969/j.issn.1672-7347.2011.02.014
- Author:
Zheng MA
1
;
Chunsheng HU
;
Yingying ZHANG
Author Information
1. Hunan Center for Disease Control and Prevention, Changsha 410005, China. 1846685@qq.com
- Publication Type:Journal Article
- MeSH:
Adult;
Chronic Disease;
Double-Blind Method;
Drugs, Chinese Herbal;
therapeutic use;
Female;
Humans;
Isodon;
chemistry;
Male;
Middle Aged;
Pharyngitis;
drug therapy;
Phytotherapy
- From:
Journal of Central South University(Medical Sciences)
2011;36(2):170-173
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To evaluate the clinical therapeutic effect of Rabdosia rubescens aqueous extract on chronic pharyngitis and its safety.
METHODS:One hundred and two patients suffered from chronic pharyngtis were randomly divided into an interventional group (n=51) and a placebo group (n=51). These volunteers were given 220 mL test materials once a day double-blindly for 30 days. All patients took routine physical examinations, and their throat symptom and pharynx signs were observed before and after the experiment.
RESULTS:After the patients had consumed Rabdosia rubescens aqueous extract and the placebo for 30 days, the improvement rates of main clinical symptom and signs in the interventional group were 67.31% and 61.54%, while those in placebo group were 19.23% and 11.54%, with significant difference (P<0.05). Before the experiment, the integral of main clinical symptom and signs between the two groups did not show significant difference (P>0.05). But after 30 days, the integral of main clinical symptom and signs in the interventional group significantly decreased (P<0.05), compared with itself before the experiment and the placebo group.
CONCLUSION:Rabdosia rubescens aqueous extract is safe and effective for patients with chronic pharyngitis.