Progress of TSC-22 gene research.
10.3969/j.issn.1672-7347.2011.07.002
- Author:
Shiming TAN
1
;
Guiyuan LI
Author Information
1. Cancer Research Institute, Central South University, Changsha 410078, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Genes, Tumor Suppressor;
Humans;
Leucine Zippers;
genetics;
Neoplasms;
physiopathology;
Repressor Proteins;
genetics;
physiology;
Transcription Factors
- From:
Journal of Central South University(Medical Sciences)
2011;36(7):592-596
- CountryChina
- Language:Chinese
-
Abstract:
Transformation growth factor β -inducible gene 22 (TSC-22) is a putative negative growth regulation and tumor suppressor gene. It has the ability to combine with other transcription factors to regulate the cell growth and apoptosis. TSC-22 is lowly expressed in many types of tumors,which may be related to the tumorgenesis and development.