Effect of anti-Helicobacter pylori on the prognosis in patients with acute cerebral infarction.
10.3969/j.issn.1672-7347.2011.09.010
- Author:
Guiqun PAN
1
Author Information
1. Department of Internal Medicine, Third People's Hospital of Yuyao,Yuyao Zhejiang, China. 635450525@qq.com
- Publication Type:Journal Article
- MeSH:
Aged;
Amoxicillin;
administration & dosage;
Anti-Bacterial Agents;
therapeutic use;
C-Reactive Protein;
analysis;
Cerebral Infarction;
drug therapy;
microbiology;
Female;
Fibrinogen;
analysis;
Helicobacter Infections;
complications;
drug therapy;
Helicobacter pylori;
Humans;
Male;
Middle Aged;
Omeprazole;
administration & dosage;
Prognosis;
Risk Factors;
Triglycerides;
blood
- From:
Journal of Central South University(Medical Sciences)
2011;36(9):872-875
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the effect of anti-Helicobacter pylori on the inflammation mediators and prognosis in patients with acute cerebral infarction.
METHODS:Routine urease test was carried out in patients with acute cerebral infarction in our hospital. The acute cerebral infarction patients with positive urease test were randomly divided into a treatment group (conventional therapy+anti-Helicobacter pylori therapy) and a control group (conventional therapy). C-reactive protein, triglycerides, and fibrinogen changes were examined before and after the treatment, symptoms of acute cerebral infarction conditions were observed,and 6-months and 1- year cerebral infarction readmission rates were measured in the 2 groups.
RESULTS:Compared with before the treatment,the C-reactive protein, triglycerides, and plasma fibrinogen decreased significantly in the treatment group, while there was no significant change in the control group. The 6-months and 1-year cerebral infarction readmission rates were significantly lower than those in the control group.
CONCLUSION:H. pylori infection may be a risk factor for cerebral infarction. A positive anti-Helicobacter pylori infection treatment can significantly improve the efficiency of cerebral infarction and reduce the short-term readmission rate.
