Omics docking and molecular classification in colorectal cancer.
10.3969/j.issn.1672-7347.2010.11.015
- Author:
Ya PENG
1
;
Shourong SHEN
Author Information
1. Department of Gastroenterology, Third Xiangya Hospital, Central South University, Changsha 410013, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Biomarkers, Tumor;
genetics;
metabolism;
Colorectal Neoplasms;
classification;
diagnosis;
genetics;
Genomics;
Humans;
Proteomics
- From:
Journal of Central South University(Medical Sciences)
2010;35(11):1201-1206
- CountryChina
- Language:Chinese
-
Abstract:
Omics docking has become a hot spot in oncology research, which is used to screen specific biomarkers for the establishment of molecular classification in the treatment and/or prognosis of diseases, especially in cancer research. Colorectal cancer (CRC) is one of the common malignant tumors, the traditional diagnosis and treatment of which depends on clinical manifestations, classic pathological and imaging examination. In clinical pathology, completely different fates and prognoses were observed in CRC patients with the same type, at the same stage, and even with the same treatment. It is critical to use the omics docking strategy to select molecular biomarkers for early diagnosis and to assess the prognosis of CRC, to further standardize molecular classification model, and to guide individual treatment of CRC.
