Mid-term and long-term clinical effect of micro-perforating trabecular surgery with amniotic membrane implants on open angle glaucoma.
- Author:
Haibo JIANG
1
;
Xiaobo XIA
;
Qilin DENG
;
Pingbao WANG
Author Information
1. Department of Ophthalmology, Xiangya Hospital, Central South University, Changsha 410008, China.
- Publication Type:Journal Article
- MeSH:
Adolescent;
Adult;
Aged;
Amnion;
transplantation;
Female;
Follow-Up Studies;
Glaucoma, Open-Angle;
surgery;
Humans;
Intraocular Pressure;
Male;
Middle Aged;
Trabeculectomy;
methods;
Treatment Outcome;
Visual Acuity;
Visual Fields;
Young Adult
- From:
Journal of Central South University(Medical Sciences)
2009;34(4):356-361
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To evaluate the mid-term and long-term clinical effect and complication of micro-perforating trabecular surgery (MPTS) with amniotic membrane implants on open angle glaucoma (OAG).
METHODS:Thirty OAG patients (49 eyes) were treated with MPTS with amniotic membrane implants. Visual acuity, intraocular pressure, visual field, type of blebs, and complications were recorded pre-and post-operatively.
RESULTS:Patients were followed up for 6~24(15.93+/-2.35) months. The mean IOPs before the operation and 24 months after the operation were (36.84+/-11.02) mmHg and (18.24+/-1.34) mmHg, respectively (P=0.000). The mean numbers of anti-glaucoma drugs used before and after the operation were (2.76+/-0.69) and (0.59+/-0.89), respectively (P<0.05). The global index of the early to moderate glaucomatous visual field loss was significantly improved postoperatively (P<0.05), and no significant difference was found in aggressive glaucoma pre- and postoperatively. Functional filter bleb was formed in 70.8% patients 24 months after the operation. The complete success rate and quality success rate were 75.5% (37/49) and 93.9% (46/49), respectively. There was no significant change in visual acuity pre- and postoperatively and no severe complication was found.
CONCLUSION:Micro-perforating trabecular surgery with amniotic membrane implants is effective and safe for OAG, with reliable effect on lowering IOP in the mid-term and long-term.
