Immunoregulatory effect of Huangqi Fuzhengtang on immunosuppressive mice.
- Author:
Xiaoli LUO
1
;
Kan YANG
;
Ming SUN
Author Information
1. Department of Cardiology, Third Xiangya Hospital, Changsha 410013, China.
- Publication Type:Journal Article
- MeSH:
Adjuvants, Immunologic;
pharmacology;
Animals;
Astragalus propinquus;
chemistry;
Drugs, Chinese Herbal;
pharmacology;
Hydrocortisone;
Immunocompromised Host;
drug effects;
immunology;
Male;
Mice;
Random Allocation;
T-Lymphocyte Subsets;
drug effects
- From:
Journal of Central South University(Medical Sciences)
2009;34(6):555-558
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To explore the immunoregulatory effect of Huangqi Fuzhengtang on immunosuppressive mice.
METHODS:The immunosuppressive mouse model was established by using hydrocortisone. Huangqi Fuzhengtang and Yupingfeng San apozema were given to the mice intragastrically. The contents of hemolysin, IL-2, and INF-gamma in the mouse serum and the expression of CD3(+), CD4(+), and CD8(+) in the peripheral blood lymphocytes were measured.
RESULTS:Huangqi Fuzhengtang could obviously elevate the contents of hemolysin, IL-2, INF-gamma and the ratio of CD4(+) and CD8+, which was more effective than Yupingfeng San.
CONCLUSION:Huangqi Fuzhengtang could improve the immune function in the immunosuppressive mice.
