Safety and efficacy of carbon dioxide insufflation during colonoscopy.
- Author:
Xiongxiang LIU
1
;
Deliang LIU
;
Jie LI
;
Dalian OU
;
Zhiyuan ZHOU
Author Information
1. Department of Gastroenterology, Second Xiangya Hospital, Central South University, Changsha 410011, China.
- Publication Type:Journal Article
- MeSH:
Abdominal Pain;
prevention & control;
Adult;
Blood Gas Monitoring, Transcutaneous;
Carbon Dioxide;
Colonoscopy;
adverse effects;
methods;
Female;
Humans;
Male;
Middle Aged;
Safety
- From:
Journal of Central South University(Medical Sciences)
2009;34(8):825-829
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To assess the safety and efficacy of carbon dioxide (CO(2)) in colonoscopy examination.
METHODS:We randomized 349 patients to undergo colonoscopy with insufflation of air (n=175) or CO(2) (n=174). At colonoscopy, p (ET CO(2)) was observed at 4 time points: before the exam, arrived caecum, back rectum, and after the exam. Patient's experience of pain in the end and after the examination at 1, 3, 6, and 24 h was registered using a visual analog scale (VAS). Sedation was not used routinely.
RESULTS:The groups were similar in age, sex, inspection time, and caecal intubation rate (all P>0.05). There were no significant differences in p (ET CO(2)) values between the 2 groups before and after the procedure (all P>0.05). VAS scores in the CO(2) group at various time points after the examination were significantly lower than those in the air group (all P<0.05). The percent of VAS scores of 0 in the CO(2) group after 1, 3, 6, and 24 h was significantly higher than that in the air group (all P<0.01).
CONCLUSION:Injection of CO(2) for colonoscopy will not cause CO(2) retention, and it may significantly reduce the pain, which is safe and effective.
