Cell surface antigen expression of orbital preadipocytes between patients with thyroid-associated ophthalmopathy and healthy adults.
- Author:
Xiang LEI
1
;
Xue-liang XU
Author Information
1. Department of Ophthalmology, Xiangya Hospital, Central South University, Changsha 410008, China.
- Publication Type:Journal Article
- MeSH:
Adipocytes;
immunology;
Adult;
Antigens, Surface;
immunology;
metabolism;
Cells, Cultured;
Female;
Graves Ophthalmopathy;
immunology;
metabolism;
HLA-DR Antigens;
immunology;
Humans;
Hyaluronan Receptors;
immunology;
Integrin beta1;
immunology;
Male;
Middle Aged;
Orbit;
immunology;
metabolism
- From:
Journal of Central South University(Medical Sciences)
2008;33(1):43-46
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the cell surface antigen expression of orbital preadipocytes between patients with thyroid-associated ophthalmopathy (TAO) and healthy adults.
METHODS:Tissue culture Methods were used in the cell culture of orbital preadipocytes in patients with TAO and healthy adults. Flow cytometry was used to analyze the expression of CD29, CD44, CD49d, and HLA-DR in these 2 cells.
RESULTS:Positive expressions were examined in orbital preadipocytes of patients with TAO and healthy adults. The orbital preadipocytes of patients with TAO had a higher expression of HLA-DR than that of healthy adults.
CONCLUSION:The orbital preadipocytes of patients with TAO and healthy adults cultured by tissue cultured Methods both belong to mesenchymal stem cells, and the former may participate in the orbital inflammation.
