Change in bone mineral density in female patients with hyperthyroidism.
- Author:
Hong ZHANG
1
;
Ai-ling YE
;
Er-yuan LIAO
Author Information
1. Institute of Metabolism and Endocrinology, Second Xiangya Hospital, Central South University, Changsha, China.
- Publication Type:Journal Article
- MeSH:
Adolescent;
Adult;
Aged;
Bone Density;
Female;
Hip Joint;
Humans;
Hyperthyroidism;
metabolism;
Lumbar Vertebrae;
Menopause;
metabolism;
Middle Aged
- From:
Journal of Central South University(Medical Sciences)
2008;33(5):452-455
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the effect of the course and menopause on the change of bone mineral density (BMD) in female patients with hyperthyroidism.
METHODS:BMDs of hip and lumbar vertebrae were measured by dual-energy X-rays absorptiometry(DEXA) in the female patients (n=192, aged 14 approximately 72). Patients were divided into 2 groups (premenopausal and postmenopausal)and 2 subgroups(short-course and long-course). The BMDs were compared between those of age-matched, weight-matched, height-matched and body mass index matched control subgroups.
RESULTS:In the premenopausal hyperthyroidic patients, only the BMDs of the second and total lumbar vertebrae with long-course were significantly lower than those of short-course group(P< 0.05). In the post-menopausal group with the long-course,each BMD measured had a lower level compared with that with short-course, of which the hip and the second lumber vertebrae were evident (P< 0.01).
CONCLUSION:The course and menopause have an effect on the BMDs in female patients with hyperthyroidism.
