Phosphoproteomics and its application in cancer research.
- Author:
Jie-Qiong LIU
1
;
Zhi-Min HE
Author Information
1. Cancer Research Institute, Central South University, Changsha 410078, China.
- Publication Type:Journal Article
- MeSH:
ErbB Receptors;
genetics;
Humans;
Neoplasms;
genetics;
metabolism;
Phosphoproteins;
genetics;
metabolism;
Phosphorylation;
Proteomics;
methods;
Signal Transduction
- From:
Journal of Central South University(Medical Sciences)
2008;33(7):559-564
- CountryChina
- Language:Chinese
-
Abstract:
Phosphoproteome is the whole complement of phosphorylated proteins in a cell, tissue or organism, and has become an interesting study subject since the discovery of phosphorylation as a key regulatory mechanism of cell life. Phosphoproteomics is a method which studies the compact of the phosphorylated proteins, expression and modification, interaction and association, rule of the regulatory and so on. Recently, phosphoproteomics is widely used in cancer research. It will provide important information in cancer research, cancer diagnosis, and therapy.
