Genetic structure of X-STR loci of Ewenki nationality and its affinity with other nationalities.
- Author:
Qiao-Fang HOU
1
;
Xiao-Zhong LI
;
Mu-Er TONG
;
Liao-Jiang RONG
;
Ran ZHANG
;
Xu-Jun WANG
;
Sheng-Bin LI
Author Information
1. Medical College of Xi'an Jiaotong University, Key Laboratory of National Ministry of Health for Forensic Sciences, Xi'an, China.
- Publication Type:Journal Article
- MeSH:
China;
Chromosomes, Human, X;
genetics;
Cluster Analysis;
Ethnic Groups;
classification;
genetics;
Female;
Gene Frequency;
Genetic Markers;
genetics;
Genetic Variation;
Genotype;
Humans;
Male;
Microsatellite Repeats;
genetics;
Phylogeny;
Polymorphism, Genetic
- From:
Journal of Central South University(Medical Sciences)
2007;32(2):276-281
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To determine the genetic diversity of X-TR loci, and to evaluate the genetic structure X chromosome's of Ewenki nationality and its affinity with other nationalities.
METHODS:We chose 9 X-TR (DXS6804, DXS7133, DXS101, DXS6789, DXS6799, DXS7423, HPRTB, DXS8378, DXS7132) as genetic markers from 99 irrelative individules to determine the genetic diversity of Ewenki in Inner Mongolian. Cluster analysis and phylogenic trees was applied to show the genetic distance among the nationalities.
RESULTS:We got 51 alleles in the studied population, with the frequency diverse between 0.0109 and 0.6863. Genotype frequency was from 0.0217 to 0.3778. Heterozygosity(H),the power of discrimination(PD) and the polymorphism information conten (PIC) were consistent with the forensic application. Cluster analysis and phylogenic trees revealed that Ewenki nationality had estrangement genetic affinity with the other 3 major nationalities in inner mongolia and Han nationality in Xi'an.
CONCLUSION:The genetic information demonstrates that the 9 chosen gene makers were highly informative loci and are suitable for population genetics research and forensic application.
