Comparison of treatment response in primary hepatocellular carcinomas with contrast-enhanced ultrasonography and contrast-enhanced helical CT.
- Author:
Ping ZHOU
1
;
Xun-Yang LIU
;
Rui-Zhen LI
;
Wan-Pin NIE
;
Sheng LIU
Author Information
1. Department of Ultrasound, Third Xiangya Hospital, Central South University, Changsha 410013, China. zhouping@hotmail.com
- Publication Type:Journal Article
- MeSH:
Adult;
Aged;
Carcinoma, Hepatocellular;
diagnostic imaging;
therapy;
Female;
Humans;
Liver Neoplasms;
diagnostic imaging;
therapy;
Male;
Middle Aged;
Tomography, Spiral Computed;
Ultrasonography
- From:
Journal of Central South University(Medical Sciences)
2007;32(4):690-694
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the value of contrast-enhanced ultra sonography for non-surgical treatment response in hepatocellular carcinomas.
METHODS:Non-surgical therapies were performed on 56 patients (64 liver neoplasms) who were diagnosed by ultrasonography-guided biopsy before the therapy. Contrast-enhanced ultrasonography(CEUS) and contrast-enhanced helical CT were performed to assess the treatment response.
RESULTS:Forty-six of the 64 lesions were not enhanced with CEUS.Partial enhancement was demonstrated in the other 18 lesions. Forty-eight of the 64 lesions were not enhanced with contrast-enhanced helical CT. Partial enhancement were demonstrated in the other 16 lesions.The sensitivity, specificity, and accuracy were 94.4%, 97.8%, and 96.9% for CEUS and 83.3%, 97.8%, and 93.8% for contrast-enhanced helical CT (P>0.05).
CONCLUSION:CEUS is a good method in assessing the non-surgical treatment response in hepatocellular carcinomas and is more sensitive and useful than contrast-enhanced helical CT in assessing the treatment response of transcatheter hepatic arterial chemoembolization.
