Clinical analysis of histocytic necrotizing lymphadenitis.
- Author:
Min-fei PEI
1
;
Xiao ZHU
;
Guang-sen ZHANG
;
Yun-xiao XU
;
Jian-kai SHEN
;
Chong-wen DAI
;
Wen-li ZHENG
;
Jun-jie YANG
Author Information
1. Department of Hematology,Second Xiangya Hospital, Central South University, Changsha 410011, China. peiminfei@tom.com
- Publication Type:Journal Article
- MeSH:
Adolescent;
Adult;
Age Factors;
Diagnosis, Differential;
Female;
Histiocytic Necrotizing Lymphadenitis;
diagnosis;
pathology;
Humans;
Lymph Nodes;
pathology;
Lymphoma;
diagnosis;
Male;
Middle Aged;
Retrospective Studies;
Sex Factors;
Tuberculosis, Lymph Node;
diagnosis
- From:
Journal of Central South University(Medical Sciences)
2006;31(1):131-133
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To understand the clinical features and histopathology of histocytic necrotizing lymphadenitis (HNL) so as to better recognize the disease.
METHODS:The clinical features, histopathology, and diagnosis of 10 patients admitted to our hospital were retrospectively analyzed.
RESULTS:The clinical features of these 10 cases included: young females were the majority; lymphadenopathy and fever were the most common clinical manifestations; some cases were accompanied by connective tissue diseases. Histopathologic examination showed distinctive necrosis and around the necrotic foci, variable proliferations of histocytes but generally without infiltration of neutrophils.
CONCLUSION:HNL has some typical histopathological alterations and relatively fine prognosis,but it tends to be misdiagnosed as lymphoma or lymphoid tuberculosis and may be accompanied by other diseases.
