Ability of catechin to eliminate O2-* and *OH.
- Author:
Xiao-jie HE
1
;
Zhu-wen YI
;
Yun TIAN
;
Xiang-yang LU
;
Xi-qiang DANG
;
Shuang-hong MO
;
Hua-bing YANG
Author Information
1. Laboratory of Pediatric Nephrology, Institute of Pediatrics, Second Xiangya Hospital, Central South University, Hunan Clinic Center of Pediatric Nephrology, Changsha. hexj7150@163.com
- Publication Type:Journal Article
- MeSH:
Antioxidants;
pharmacology;
Catechin;
pharmacology;
Free Radical Scavengers;
pharmacology;
Hydroxyl Radical;
metabolism;
Luminescent Measurements;
Superoxides;
metabolism
- From:
Journal of Central South University(Medical Sciences)
2006;31(1):138-140
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the eliminating ability of catechin to eliminate O2-* and *OH.
METHODS:The ability of catechin to clear away O2-* and *OH was respectively measured by faintness chemiluminescence and spin trapping assay.
RESULTS:IC50 that catechin eliminated O2-* and *OH was 6.16, 0.59 g/mL respectively, and the eliminating ability of catechin was much stronger than that of the extract from liquorice, rosemary, grape pip, giant knotweed and ginkgo leaf.
CONCLUSION:Compared with several important natural plants of antioxidants, the eliminating ability of cathechin is the best.