Effect of lamivudine treatment on the quality of life of chronic hepatitis B.
- Author:
Lu-xi YI
1
;
Xu YANG
;
Xiao-wan WANG
Author Information
1. Department of Infectious Disease, Second Xiangya Hospital, Central South University, Changsha, China. hongmeil@hotmail.com
- Publication Type:Journal Article
- MeSH:
Female;
Hepatitis B, Chronic;
drug therapy;
psychology;
Humans;
Lamivudine;
therapeutic use;
Male;
Quality of Life;
Reverse Transcriptase Inhibitors;
therapeutic use;
Surveys and Questionnaires
- From:
Journal of Central South University(Medical Sciences)
2006;31(3):396-399
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To assess the quality of life of 3 types of chronic hepatitis B before and after the treatment of lamivudine, and to find an ideal way of medical treatment for chronic hepatitis B.
METHODS:One hundred and fifty patients with chronic hepatitis B were investigated in this study, among whom 5 1 were in mild state illness, 53 were middle-range and the other 46 were severe. The quality of life of the patients was assessed by the quality of life questionnaire (SF-36). The marks of questionnaire were compared before and after the use of lamivudine to assess its comprehensive curative effect on chronic hepatitis B.
RESULTS:The total score of SF-36, score of physical function, role-physical, mental health, social function, bodily pain and vitality were significant different before and after the treatment. Statistically significant differences were found among the 3 types of chronic hepatitis B before and after the treatment.
CONCLUSION:The quality of life of patients with chronic hepatitis B can be improved by using lamivudine. Assessment of quality of life may be taken as an important index in treating chronic hepatitis B.
