Two Cases of Microscopic Polyangiitis.
10.4046/trd.2003.55.6.623
- Author:
Kyoung Eun SONG
1
;
Seung Guan IM
;
Sook Kyoung JO
;
Youn Mu JUNG
;
Joon Hyuck CHOI
;
Seung Soo SHEEN
;
Yoon Jung OH
;
Kwang Joo PARK
;
Sung Chul HWANG
;
Hyun Ee YIM
Author Information
1. Department of Pulmonary and Critical Care Medicine, Ajou University School of Medicine, Suwon, Korea. schwang@ajou.ac.kr
- Publication Type:Case Report
- Keywords:
Microscopic polyangiitis;
ANCA;
CNS vasculitis;
Diffuse alveolar hemorrhage syndrome
- MeSH:
Antibodies, Antineutrophil Cytoplasmic;
Central Nervous System;
Glomerulonephritis;
Hemorrhage;
Humans;
Lung;
Microscopic Polyangiitis*;
Polyarteritis Nodosa;
Recurrence;
Vasculitis;
Vasculitis, Central Nervous System
- From:Tuberculosis and Respiratory Diseases
2003;55(6):623-630
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Microscopic polyangiitis is a systemic small-vessel vasculitis that is primarily associated with necrotizing glomerulonephritis and pulmonary capillaritis. Lung involvement is characterized by a diffuse alveolar hemorrhage. However, rarely central nervous system involvement has been reported to be occurred with the microscopic polyangiitis. Relapse of microscopic polyangiitis are reported to be more frequent than those of polyarteritis nodosa, often after a reduction or discontinuation of the therapy. We would like to report two patients with microscopic polyangiitis. One presented with clinical manifestations of both lung and central nervous system involvements and the other was a case of recurrence during steroid tapering following the steroid pulse therapy.