Analysis of 92 ectopic pregnancy patients after in vitro fertilization and embryo transfer.
- Author:
Hong-mei XIAO
1
;
Fei GONG
;
Zeng-hui MAO
;
Hong ZHANG
;
Guang-xiu LU
Author Information
1. Institute of Reproduction and Stem Cell Engineering, Central South University, Reproductive and Genetic Hospital of CITIC-XIANGYA, Changsha 410078, China.
- Publication Type:Journal Article
- MeSH:
Adult;
China;
epidemiology;
Embryo Transfer;
adverse effects;
Female;
Fertilization in Vitro;
adverse effects;
Humans;
Infertility, Female;
Middle Aged;
Pregnancy;
Pregnancy, Ectopic;
epidemiology;
etiology;
Retrospective Studies;
Sperm Injections, Intracytoplasmic
- From:
Journal of Central South University(Medical Sciences)
2006;31(4):584-587
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the occurrence of ectopic pregnancy among women who received in vitro fertilization and assess the influential factors.
METHODS:The indications, methods of assisted conception and ectopic types were analyzed retrospectively after the patients received in vitro fertilization and embryo transfer (IVF-ET), intracytoplasmic sperm injection (ICSI), or freezing-thawing embryo transfer (FET).
RESULTS:A total of 6007 embryo transfers were performed, and 2322 (38.7%) clinical pregnancies were obtained. Ninety-four (4.05%) of them were ectopic pregnancies; and 92 were tubal pregnancies. The occurrence rate was 3.96%, which constituted 97.87% (92/94) of all ectopic pregnancies. There were 2 cases of other parts: one in abdominal cavity and the other in cornual pregnancy with the occurrence rate of 0.86%, constituting 2.32% (2/94). Twenty heterotopic pregnancies occurred (0.86%), constituting 21.28% (20/94). Among all ectopic pregnancies, the assisted conception of 86 cases was tubal pathology and/or pelvic adherence (91.49%), and 24 patients had a history of ectopic pregnancy (25.53%). The differences of clinical pregnancy rates between IVF-ET, ICSI and FET were not significant (P>0.05). The ectopic rate of IVF-ET group was significantly higher than that of ICSI or FET group (P<0.05), respectively. The ectopic rate in FET group was also higher than that in ICSI group (P<0.05).
CONCLUSION:The occurrence rate of ectopic pregnancy after IVF is higher than that of spontaneous pregnancy, and the main cause for ectopic pregnancy is the tubal pathological changes.
