Genetic Heterogeneity in 56 kDa gene of Orientia tsutsugamushi Genotype Karp.
- Author:
Woo Hyun CHANG
;
Sun Ho KEE
;
Hyun Jae SONG
- Publication Type:Original Article
- MeSH:
Genetic Heterogeneity*;
Genotype*;
Orientia tsutsugamushi*;
Polymerase Chain Reaction;
Rodentia;
Sequence Analysis
- From:Journal of the Korean Society for Microbiology
1997;32(4):415-420
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The type-specific PCR and the sequence analysis of 56 kDa gene of Orientia tsutsugamushi infected in field rodents specimens have shown intratypic genetic heterogeneity in genotype Karp. In sequence comparison, this genetic heterogeneity was mainly due to insertion or deletion of a repeated unit in variable domain I (VDI) region. These results suggested that genetic duplication or deletion of the specific sequence rnight be involved in intratypic genetic heterogeneity of Orientia tsutsugamushi.
