Risk factors for metastasis and recurrence of hepatocellular carcinoma at different stages.
- Author:
Di-Peng OU
1
;
Lian-Yue YANG
;
Geng-Wen HUANG
;
Yi-Ming TAO
;
Xiang DING
;
Zhi-Gang CHANG
Author Information
1. Liver Cancer Laboratory, Department of Surgery, Xiangya Hospital, Central South University, Changsha 410008, China. Lianyueyang@hotmail.com
- Publication Type:Journal Article
- MeSH:
Adult;
Carcinoma, Hepatocellular;
surgery;
China;
epidemiology;
Female;
Follow-Up Studies;
Hepatectomy;
Humans;
Liver Neoplasms;
surgery;
Lymphatic Metastasis;
Male;
Middle Aged;
Neoplasm Recurrence, Local;
epidemiology;
Postoperative Period;
Retrospective Studies;
Risk Factors
- From:
Journal of Central South University(Medical Sciences)
2005;30(5):540-543
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To analyze the risk factors for metastasis and recurrence of hepatocellular carcinoma (HCC) postoperatively.
METHODS:Data of 270 cases of postoperative HCC were analyzed by SPSS software retrospectively.
RESULTS:Out of the 270 cases, 162 got follow-up study and 136 showed metastasis and recurrence. Lots of risk factors induced the recurrence of HCC, such as AFP, tumor form, venous blood invasion, HBV infection, resection dimension and perioperative transfusion. There were different risk factors at different stages.
CONCLUSION:The early recurrence of HCC may be mediated by macro- or micro-vessel blood invasion and metastasis, the late recurrence by multicentric carcinogenesis or introhepatic cacinoma de novo.