Assessment of left ventricular systolic and diastolic function by Doppler tissue imaging in patients with chronic heart failure.
- Author:
Sai-dan ZHANG
1
;
Sheng-ling ZHANG
;
Hong-yan ZHOU
;
Hui-ying LI
;
Qing-jun GUI
Author Information
1. Department of Cardiology, Xiangya Hospital, Changsha 410008, China. Zhangsaidanli@126.com
- Publication Type:Journal Article
- MeSH:
Diastole;
Echocardiography, Doppler, Pulsed;
Female;
Heart Failure;
diagnostic imaging;
physiopathology;
Humans;
Male;
Systole;
Ventricular Function, Left;
physiology
- From:
Journal of Central South University(Medical Sciences)
2005;30(1):60-63
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the application of pulsed-wave Doppler tissue imaging ( PW-DTI) in evaluating left ventricular systolic and diastolic function in patients with chronic heart failure (CHF).
METHODS:Mitral annular velocities (MAV) were measured by PW-DTI in 35 patients with CHF and 25 healthy subjects. Traditional indices for evaluating the global left ventricular function by conventional echocardiography were also studied as a comparison.
RESULTS:Peak systolic, peak early diastolic, peak late diastolic mitral annular velocities ( Sa, Ea, Aa), and Ea/Aa ratio progressively decreased in CHF patients compared with the healthy subjects (P <0.01 ). Sa of the mitral annulus correlated linearly with the left ventricle ejection fraction (LVEF) (r =0.890, P < 0.01). Compared with the healthy subjects, Ea in all 3 subgroups of diastolic dysfunction in the CHF group significantly decreased (P <0.01). Aa in 2 subgroups (pseudonormal filling and restrictive filling) decreased (P < 0.01 ) and the decreased Ea/Aa was found in the delayed relaxation and pseudonormal filling subgroups compared with the healthy subjects (P<0.001).
CONCLUSION:MAV measured by PW-DTI can be used for assessing the left ventricular systolic and diastolic function in CHF patients.