Sensitivity of nanoparticlized cefazolin sodium to the bacteria in vitro.
- Author:
Long ZOU
1
;
Xue-Gong FAN
;
Hui GUI
Author Information
1. Department of Infectious Diseases, Xiangya Hospital, Central South University, Changsha 410008, China.
- Publication Type:Journal Article
- MeSH:
Anti-Bacterial Agents;
pharmacology;
Cefazolin;
pharmacology;
Escherichia coli;
drug effects;
Microbial Sensitivity Tests;
Nanostructures;
Staphylococcus aureus;
drug effects
- From:
Journal of Central South University(Medical Sciences)
2005;30(3):318-320
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate whether the in vitro sensitivity of cefazolin sodium to the bacteria was altered after nanoparticlization.
METHODS:The minimal inhibitory concentrations (MIC) of cefazolin sodium before and after nanoparticlization to S. aureaus and E. coli. were determined by microdilution.
RESULTS:The MIC of nanoparticlized cefazolin sodium to S. aureaus and E. coli. had no significant change compared with that of non-nanoparticlized one.
CONCLUSION:Nanoparticlization will not decrease the sensitivity of cefazolin sodium to the bacteria.
