Role of sulforaphane in improving negative symptoms and cognitive symptoms of schizophrenia and the underlying mechanism.
10.11817/j.issn.1672-7347.2019.06.014
- Author:
Ye YANG
1
;
Ranran LI
1
;
Gangrui HEI
1
;
Renrong WU
1
Author Information
1. Department of Psychiatry, Second Xiangya Hospital, Central South University, Changsha 410011, China.
- Publication Type:Journal Article
- MeSH:
Cognition;
Humans;
Isothiocyanates;
therapeutic use;
Schizophrenia;
drug therapy
- From:
Journal of Central South University(Medical Sciences)
2019;44(6):701-705
- CountryChina
- Language:Chinese
-
Abstract:
The negative symptoms and cognitive symptoms of schizophrenia patients are still clinical problems to be solved. Schizophrenia patients are abnormal in oxidative stress, immune regulation, and anti-histone deacetylase (HDAC), while sulforaphane plays a role in anti-oxidative stress, anti-inflammation, and anti-HDAC. Therefore, the sulforaphane could improve the negative symptoms and cognitive deficits of schizophrenia.
