Remineralization of demineralized dentin induced by bioactive glass NovaMin.
10.11817/j.issn.1672-7347.2018.06.007
- Author:
Xiansheng HUANG
1
;
Rong LI
2
;
Yunzhi FENG
2
;
Yining WANG
3
Author Information
1. Department of Cardiovascular Medicine, Second Xiangya Hospital, Central South University, Changsha 410011, China.
2. Department of Stomatology, Second Xiangya Hospital, Central South University, Changsha 410011, China.
3. Department of Prosthodontics, School of Stomatology, Wuhan University, Wuhan 430079, China.
- Publication Type:Journal Article
- MeSH:
Dental Pulp Cavity;
Dentin;
chemistry;
Glass;
Microscopy, Electron, Scanning;
Saliva, Artificial;
Spectroscopy, Fourier Transform Infrared;
Tooth Remineralization;
methods
- From:
Journal of Central South University(Medical Sciences)
2018;43(6):619-624
- CountryChina
- Language:Chinese
-
Abstract:
To explore the remineralization effect of bioactive glass NovaMin on demineralized dentin specimens, and to study the physical and chemical properties of formed structure at dentin surface.
Methods: One mm-thickness coronal dentin slices were soaked in ethylene diamine tetraacetic acid (EDTA) for 48 h to prepare the completely demineralized dentin specimens and they were divided into 2 groups: an artificial saliva group (control group) and a NovaMin powder group. The specimens were treated with artificial saliva or NovaMin powder for 2 min (2 times every day), and the interval was 8 hours. Then, the specimens were soaked in the remineralization solution. After 7 days, the scanning electron microscope (SEM), energy dispersive X-ray (EDX), attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) and X-ray diffraction (XRD) were used to detect dentin morphology, the physical and chemical properties of the formed structure at dentin surface.
Results: The results of SEM showed that a defined surface layer in the NovaMin powder group could be observed in the SEM imaging at the 7th day, which completely occluded dentinal tubules; the EDX, ATR-FTIR and XRD analysis found that the mineralized layer formed at dentin surface was mainly composed of calcium and phosphate elements, which was similar to the hydroxyapatite-like crystal. However, there were no materials formed at the dentin surface in the control group, and the dentinal tubules were still open.
Conclusion: NovaMin can remineralize the demineralized dentin specimens and occlude the dentinal tubules in hydroxyapatite-like crystal structure.
