Apolipoprotein A5 gene polymorphisms affect triglyceride metabolism and atherosclerotic cardiovascular diseases.
10.11817/j.issn.1672-7347.2018.12.012
- Author:
Yaqiong LIU
1
;
Wang ZHAO
1
;
Shuiping ZHAO
1
Author Information
1. Department of Cardiovascular Medicine, Second Xiangya Hospital, Central South University, Changsha 410011, China.
- Publication Type:Journal Article
- MeSH:
Apolipoprotein A-V;
genetics;
Atherosclerosis;
genetics;
Gene Frequency;
Humans;
Polymorphism, Genetic;
Polymorphism, Single Nucleotide;
Triglycerides;
metabolism
- From:
Journal of Central South University(Medical Sciences)
2018;43(12):1358-1363
- CountryChina
- Language:Chinese
-
Abstract:
Apolipoprotein A5 (Apo A5) is a novel member in apolipoprotein family, which is proven to be an important regulator in triglyceride metabolism, especially in adjusting the TG content in plasma. Apo A5 gene polymorphisms affect triglyceride metabolism and atherosclerotic cardiovascular diseases. The research focuses on -1131T>C, c.56C>G, and c.553G>T.
