Salivary cortisol level and peri-abortion depression.
10.11817/j.issn.1672-7347.2019.190407
- Author:
Xiaohong ZHANG
1
;
Jiangming SHENG
2
;
Chi HUANG
3
;
Altangarvdi BORJIGEN
3
;
Mengxiang LIU
3
;
Huiting PENG
3
;
Chunxiang QIN
4
Author Information
1. Department of Emergency, Third Xiangya Hospital, Central South University, Changsha 410013, China.
2. Departmentof Geriatric, Second Xiangya Hospital, Central South University, Changsha 410011, China.
3. Xiangya Nursing School, Central South University, Changsha 410013, China.
4. Department of Obstetrics, Third Xiangya Hospital, Central South University, Changsha 410013, China.
- Publication Type:Journal Article
- MeSH:
Depression;
Depressive Disorder;
metabolism;
Female;
Humans;
Hydrocortisone;
metabolism;
Pregnancy;
Prospective Studies;
Saliva;
metabolism
- From:
Journal of Central South University(Medical Sciences)
2019;44(9):1023-1029
- CountryChina
- Language:Chinese
-
Abstract:
To study the salivary cortisol level, and to analyze the correlation between salivary cortisol and peri-abortion depression in the women suffering termination of pregnancy for fetal anomaly.
Methods: Comparing the difference in salivary cortisol level between the women with and without depression when they underwent termination of pregnancy for fetal anomaly in a prospective cohort study. Analyzing the correlation between salivary cortisol and peri-abortion depression through logistics regression analysis.
Results: The salivary cortisol awakening response was lower in women with depression than women without depression. Based on the logistics regression analysis, the salivary cortisol awakening response showed a negative correlation with pre-abortion (OR=0.063, 95% CI 0.005 to 0.754) and post-abortion (OR=0.002, 95% CI 0.000 to 0.061) depression.
Conclusion: Cortisol awakening response possesses a negative correlation with peri-abortion depression, and it is a predictive factor for post-abortion depression.
