Successful simultaneous surgery for patient with insulinoma and parathyroid adenoma relevant to multiple endocrine neoplasia type 1: A case report.
10.11817/j.issn.1672-7347.2019.190601
- Author:
Baojian HOU
1
,
2
;
Weili TANG
1
,
3
;
Xin SU
1
,
3
;
Wei LIU
1
,
3
Author Information
1. Department of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, Changsha 410011
2. Department of Metabolism and Endocrinology, Zhongshan Hospital in Hubei Province, Wuhan 430033, China.
3. National Clinical Research Center for Metabolic Diseases, Changsha 410011, China.
- Publication Type:Case Reports
- MeSH:
Adult;
Humans;
Insulinoma;
Male;
Multiple Endocrine Neoplasia Type 1;
Pancreatic Neoplasms;
Parathyroid Neoplasms;
Parathyroidectomy
- From:
Journal of Central South University(Medical Sciences)
2019;44(9):1083-1088
- CountryChina
- Language:Chinese
-
Abstract:
Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder. A 44-year-old man visited second Xiangya Hospital, Central South University due to hypoglycemia. He was eventually diagnosed as MEN1. A novel homozygous frameshift for c.640-643delCAGA (p.V215Mfs*13) of MEN1 gene was identified in the patient. After MDT (Multiple Disciplinary Team), open bilateral exploration with total parathyroidectomy and autotransplantation as well as partial pancreatectomy excision of all the macroscopic pancreatic tumors were performed at the same time. The patient recovered well. Individualized diagnosis and treatment are important for MEN1 patients.
